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Pick your adjective — enormous, astronomical, colossal. The political spending in 2012 was unprecedented and already has implications for the next campaign cycle.

The Obama campaign on Wednesday escalated its attack on Mitt Romney's business career, with Vice President Joe Biden scheduled to aggressively question how Romney's management of the private equity firm Bain Capital might translate into running the U.S. economy.

Job growth was weak, but the jobless rate edged down from 8.2 percent in March.

Years after more than 40 patients with HIV received immune cells designed to attack and kill cells infected with HIV, the specialized cells are still present in their bloodstreams. There's been no sign the cells, a form of gene therapy, caused any serious side effects.

The Chinese women's Olympic volleyball coach blamed his team's recent losses on their lack of access to safe meat while on the road. A lot of meat that's served in China is tainted with a chemical that's also considered a performance-enhancing drug.

The U.S. women's gymnastics team has won the team gold medal at the London 2012 Olympics, handily beating Russia, which took silver, and Romania, which took bronze. China finished fourth.

Each month this year, builders have been starting work on many more homes than were being built after the housing bubble burst in 2008. Meanwhile, sales and prices of previously owned homes continue to rise.

Republican presidential nominee Mitt Romney campaigned with veterans in Northern Virginia on Thursday. And like President Obama, he was in territory that voted for the opposite party four years ago.

Athletic conferences don't make much sense anymore. Commentator Frank Deford remarks on how the Big East conference is no longer as big or as east as it used to be.

How aggressive will Biden be? How will Ryan handle the biggest stage he's been on?