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U.S. issues order targeting Israeli settlers who attack West Bank Palestinians. South Carolina hosts the Democratic primary Saturday. The anniversary of a train derailment in Ohio is Saturday.

President Biden and former President Trump agree to two debates. White House explains differences between arms shipments to Israel. Slovakia's prime minister recovers from an assassination attempt.

NPR's Scott Detrow speaks with NASA administrator Bill Nelson about the space agency's plans to return to the moon and travel later to Mars.

An Israeli strike hit a food distribution center, killing a U.N. relief worker — a sign of the heightened dangers and challenges of bringing much-needed aid into Gaza during the war.

French authorities indict Telegram founder on multiple charges. Donald Trump shares TikTok video including footage that may violate federal law. Republicans insist noncitizens will sway the election.

President Biden's news conference monitored for mistakes. After Biden-Trump debate, poll on presidential race is out. Palestinians who fled parts of Gaza City return to find little left of their homes.

U.S. Navy continues to fire missiles at Houthi fighters in Yemen. After Iowa, only three major GOP presidential candidates remain. Supreme Court to hear case that could weaken federal rule making.

Israel's military says it has been battling Hamas fighters around Gaza's hospitals. President Biden this week attends a summit of Asian leaders. U.S. government funding is set to run out on Friday.

Two initiatives in Gaza are on a collision course. Supreme Court hears a case that may help define the internet's future. Congress faces another shutdown deadline on Friday.

Israel's prime minister will speak to a joint meeting of Congress. The rapid-fire launch of Kamala Harris' presidential campaign. A new NPR poll shows more voters moved into the undecided camp.